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Tertiary Respiratory Center
Department of Pulmonary Medicine, Andhra Medical College, Visakhapatnam.

Pulmonary Tuberculosis

Pulmonary Tuberculosis

Pulmonary Tuberculosis (TB) is a contagious bacterial infection primarily affecting the lungs, caused by Mycobacterium tuberculosis. This airborne disease spreads when an infected person coughs or sneezes, releasing bacteria into the air, which can then be inhaled by others. Pulmonary TB is characterized by a persistent cough lasting more than three weeks, often producing bloody or sputum, chest pain, fatigue, fever, night sweats, and unexplained weight loss. While TB can affect other parts of the body, pulmonary TB is the most common and is particularly concerning due to its potential to spread to others. Without treatment, TB can cause significant lung damage and can be fatal.

Treatment for Pulmonary Tuberculosis

Treatment for Pulmonary Tuberculosis involves a prolonged course of antibiotics, typically lasting six to nine months. The standard treatment regimen includes a combination of first-line anti-TB medications such as isoniazid, rifampicin, pyrazinamide, and ethambutol. Adherence to the full course of treatment is crucial to cure the infection, prevent the development of drug-resistant TB, and reduce the risk of spreading the disease to others. In cases of multidrug-resistant TB (MDR-TB), where the bacteria are resistant to first-line drugs, treatment is longer and involves second-line medications, which may have more side effects. Directly observed therapy (DOT) is often recommended to ensure patients take their medication correctly. Alongside medication, supportive care, good nutrition, and monitoring for side effects are essential components of successful treatment. Public health measures, including screening and vaccination with the Bacillus Calmette-Guérin (BCG) vaccine in some countries, are critical in preventing the spread of TB.

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