Malaria is a life-threatening disease caused by Plasmodium parasites, which are transmitted to humans through the bites of infected female Anopheles mosquitoes. The most common and deadly species is Plasmodium falciparum, but other species like Plasmodium vivax, Plasmodium ovale, and Plasmodium malaria also cause malaria. Symptoms of malaria typically appear 10-15 days after the mosquito bite and include fever, chills, headache, muscle aches, and fatigue. In severe cases, malaria can cause complications such as anemia, organ failure, and cerebral malaria, which can be fatal if not treated promptly.
Treatment for malaria depends on the type of Plasmodium parasite and the severity of the infection. For uncomplicated malaria, especially caused by P. falciparum, the World Health Organization (WHO) recommends artemisinin-based combination therapies (ACTs) as the first-line treatment. Other medications, such as chloroquine, are used for non-falciparum malaria, like that caused by P. vivax. In severe cases of malaria, intravenous administration of artesunate is recommended, followed by a full course of ACTs once the patient can tolerate oral medication.
Preventive measures, including the use of insecticide-treated bed nets, indoor spraying with insecticides, and antimalarial prophylaxis for travelers to endemic areas, are crucial in controlling and reducing the spread of malaria.